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When I assign to the Shift, Ctrl and Shift + Ctrl and the middle mouse button shortcut any command that requires selecting a point on the screen, running a command via a mouse shortcut causes the _TK (multiple temporary tracking points) command to be added before selecting the point. This behavior of the program makes using such commands with the middle mouse button meaningless.
The command assigned to the shortcut is executed, but the indication of the first point is preceded by _TK.
Needless to say, I got used to the layout of mouse shortcuts over the years and I don't understand how you could mess it up.
Version 21.2.05 (x64) revision c77687b2